Engineering Macromolecular Architectures for Targeted Applications

New Approaches Towards the Design of Tough Amphiphilic Polymeric Co-networks

Shereen Tan, Nicholas Jun-An Chan, Joe Collins, Qiang Fu, Greg G Qiao

2020-01-01

Tunable, Quantitative Fenton-RAFT Polymerization via Metered Reagent Addition

MD Nothling, TG McKenzie, A Reyhani, GG Qiao

2018-10-01

A continuous supply of radical species is a key requirement for activating chain growth and accessing quantitative monomer convers..

Blood-Catalyzed RAFT Polymerization

A Reyhani, MD Nothling, H Ranji-Burachaloo, TG McKenzie, Q Fu, S Tan, G Bryant, GG Qiao

2018-08-06

The use of hemoglobin (Hb) contained within red blood cells to drive a controlled radical polymerization via a reversible addition..

Blood‐Catalyzed RAFT Polymerization

Amin Reyhani, Mitchell D Nothling, Hadi Ranji‐Burachaloo, Thomas G McKenzie, Qiang Fu, Shereen Tan, Gary Bryant, Greg G Qiao

2018-08-06

<jats:title>Abstract</jats:title><jats:p>The use of hemoglobin (Hb) contained within red blood cells to drive a controlled radical..

Biocompatible porous polyester-ether hydrogel scaffolds with cross-linker mediated biodegradation and mechanical properties for tissue augmentation

B Ozcelik, J Palmer, K Ladewig, PF Marina, GW Stevens, K Abberton, WA Morrison, A Blencowe, GG Qiao

2018-02-12

Porous polyester-ether hydrogel scaffolds (PEHs) were fabricated using acid chloride/alcohol chemistry and a salt templating appro..

Sono-RAFT Polymerization in Aqueous Medium

TG McKenzie, E Colombo, Q Fu, M Ashokkumar, GG Qiao

2017-09-25

The ultrasonic irradiation of aqueous solution is demonstrated to be a suitable source of initiating radicals for a controlled rad..

Sono‐RAFT Polymerization in Aqueous Medium

Thomas G McKenzie, Enrico Colombo, Qiang Fu, Muthupandian Ashokkumar, Greg G Qiao

2017-09-25

The ultrasonic irradiation of aqueous solution is demonstrated to be a suitable source of initiating radicals for a controlled rad..

Tuning the Properties of Polymer Capsules for Cellular Interactions

H Sun, J Cui, Y Ju, X Chen, EHH Wong, J Tran, GG Qiao, F Caruso

2017-07-19

Particle-cell interactions are governed by, among other factors, the composition and surface properties of the particles. Herein, ..

Fenton-RAFT Polymerization: An “On-Demand” Chain-Growth Method

A Reyhani, TG McKenzie, H Ranji-Burachaloo, Q Fu, GG Qiao

2017-05-29

Fine control over the architecture and/or microstructure of synthetic polymers is fast becoming a reality owing to the development..

Antifogging Surface Facilitated by Nanoscale Coatings with Controllable Hydrophobicity and Cross-Linking Density

E Nam, EHH Wong, S Tan, Q Fu, A Blencowe, GG Qiao

2017-01-01

Antifogging and frost-resistant coatings can be used in a wide range of applications and enable high light transmission through su..

Bionano Interaction Study on Antimicrobial Star-Shaped Peptide Polymer Nanoparticles

SJ Lam, EHH Wong, NM O'Brien-Simpson, N Pantarat, A Blencowe, EC Reynolds, GG Qiao

2016-12-14

'Structurally nanoengineered antimicrobial peptide polymers' (SNAPPs), in the form of star-shaped peptide polymer nanoparticles, h..

Observed Photoenhancement of RAFT Polymerizations under Fume Hood Lighting

LPM Da Costa, TG McKenzie, KN Schwarz, Q Fu, GG Qiao

2016-11-15

Given the recent findings of exogenous radical initiator/catalyst-free reversible addition-fragmentation chain transfer (RAFT) rad..

CO2 separation using surface-functionalized SiO2 nanoparticles incorporated ultra-thin film composite mixed matrix membranes for post-combustion carbon capture

J Kim, Q Fu, K Xie, JMP Scofield, SE Kentish, GG Qiao

2016-10-01

CO<inf>2</inf> separation across polyethylene glycol (PEG)-based ultra-thin film composite mixed matrix membranes (UTFC-MMMs) cont..

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

SJ Lam, NM O'Brien-Simpson, N Pantarat, A Sulistio, EHH Wong, YY Chen, JC Lenzo, JA Holden, A Blencowe, EC Reynolds, GG Qiao

2016-09-12

With the recent emergence of reports on resistant Gram-negative 'superbugs', infections caused by multidrug-resistant (MDR) Gram-n..

Beyond Traditional RAFT: Alternative Activation of Thiocarbonylthio Compounds for Controlled Polymerization

TG McKenzie, Q Fu, M Uchiyama, K Satoh, J Xu, C Boyer, M Kamigaito, GG Qiao

2016-09-01

Recent developments in polymerization reactions utilizing thiocarbonylthio compounds have highlighted the surprising versatility o..

Blends of Fluorinated Additives with Highly Selective Thin-Film Composite Membranes to Increase CO2 Permeability for CO2/N2 Gas Separation Applications

JMP Scofield, PA Gurr, J Kim, Q Fu, SE Kentish, GG Qiao

2016-08-03

A highly permeable poly(ethylene glycol-b-pentafluoropropyl acrylate) diblock copolymer additive is blended with the highly select..

Investigation into the photolytic stability of RAFT agents and the implications for photopolymerization reactions

TG McKenzie, LPM Da Costa, Q Fu, DE Dunstan, GG Qiao

2016-07-07

The photolytic stability of various RAFT agents (i.e., thiocarbonylthio-containing compounds) under irradiation from a blue LED li..

Star Polymers

JM Ren, TG McKenzie, Q Fu, EHH Wong, J Xu, Z An, S Shanmugam, TP Davis, C Boyer, GG Qiao

2016-06-22

Recent advances in controlled/living polymerization techniques and highly efficient coupling chemistries have enabled the facile s..

Spatial-controlled nanoengineered films prepared: Via rapid catalyst induced cross-linking

E Nam, EHH Wong, S Tan, SN Guntari, Q Fu, J Kim, B Delalat, A Blencowe, GG Qiao

2016-05-21

A new top-down approach to generate stable nanoscale films via catalyst induced cross-linking (CIC) is demonstrated. Polymers with..

Polypeptide-Based Macroporous Cryogels with Inherent Antimicrobial Properties: The Importance of a Macroporous Structure

SJ Shirbin, SJ Lam, NJA Chan, MM Ozmen, Q Fu, N O'Brien-Simpson, EC Reynolds, GG Qiao

2016-05-17

Synthetic polypeptide-based macroporous cryogels with inherent antimicrobial properties were prepared for potential water purifica..

Ultra-thin film composite mixed matrix membranes incorporating iron(III)-dopamine nanoparticles for CO2 separation

J Kim, Q Fu, JMP Scofield, SE Kentish, GG Qiao

2016-04-21

Iron dopamine nanoparticles (FeDA NPs) are incorporated into a nanoscale thick polyethylene glycol (PEG) matrix for the first time..

Photocontrolled Cargo Release from Dual Cross-Linked Polymer Particles

S Tan, J Cui, Q Fu, E Nam, K Ladewig, JM Ren, EHH Wong, F Caruso, A Blencowe, GG Qiao

2016-03-09

Burst release of a payload from polymeric particles upon photoirradiation was engineered by altering the cross-linking density. Th..

A novel solid state photocatalyst for living radical polymerization under UV irradiation

Q Fu, TG McKenzie, JM Ren, S Tan, E Nam, GG Qiao

2016-02-11

This study presents the development of a novel solid state photocatalyst for the photoinduced controlled radical polymerization of..

Stereoregular High-Density Bottlebrush Polymer and Its Organic Nanocrystal Stereocomplex through Triple-Helix Formation

JM Ren, K Ishitake, K Satoh, A Blencowe, Q Fu, EHH Wong, M Kamigaito, GG Qiao

2016-02-09

We report the synthesis of a well-defined molecular bottlebrush polymer with stereoregular side chains (i.e., syndiotactic PMMA). ..

Development of Novel Fluorinated Additives for High Performance CO2 Separation Thin-film Composite Membranes

JMP Scofield, P Gurr, J Kim, Q Fu, null Kentish, G QIao

2016-02-01

A series of poly(ethylene glycol)-block-poly(pentafluoropropyl acrylate) diblock copolymers were synthesized by Reversible Additio..

A novel cross-linked nano-coating for carbon dioxide capture

Q Fu, J Kim, PA Gurr, JMP Scofield, SE Kentish, GG Qiao

2016-01-01

Ultra-thin ([similar]100 nm) films with uniform thicknesses can facilitate high CO2 permeation and are of potential technological ..

Synthesis of high-order multiblock core cross-linked star polymers

TG McKenzie, JM Ren, DE Dunstan, EHH Wong, GG Qiao

2016-01-01

Core cross-linked star (CCS) polymers with radiating arms composed of high-order multiblock copolymers have been synthesized in a ..

Structure Governs the Deformability of Polymer Particles in a Microfluidic Blood Capillary Model

H Sun, M Björnmalm, J Cui, EHH Wong, Y Dai, Q Dai, GG Qiao, F Caruso

2015-10-19

Particle stiffness is a design parameter that affects bionano interactions, including biodistribution kinetics and cellular proces..

Amphiphilic core cross-linked star polymers as water-soluble, biocompatible and biodegradable unimolecular carriers for hydrophobic drugs

D Gu, K Ladewig, M Klimak, D Haylock, KM McLean, AJ O'Connor, GG Qiao

2015-09-28

Unimolecular polymeric architectures are ideal candidates for drug encapsulation. In this study we report the facile yet well-cont..

Controlled Formation of Star Polymer Nanoparticles via Visible Light Photopolymerization

TG McKenzie, EHH Wong, Q Fu, A Sulistio, DE Dunstan, GG Qiao

2015-09-15

A recently developed visible light mediated photocontrolled radical polymerization technique using trithiocarbonates (i.e., conven..

Tertiary amine catalyzed photo-induced controlled radical polymerization of methacrylates

Q Fu, TG McKenzie, S Tan, E Nam, GG Qiao

2015-08-14

A novel tertiary amine catalyst (TAC) and trithiocarbonate (TTC) synergistic photo-induced controlled radical polymerization of me..

Cisplatin-Induced Formation of Biocompatible and Biodegradable Polypeptide-Based Vesicles for Targeted Anticancer Drug Delivery

SJ Shirbin, K Ladewig, Q Fu, M Klimak, X Zhang, W Duan, GG Qiao

2015-08-10

Novel cisplatin (CDDP)-loaded, polypeptide-based vesicles for the targeted delivery of cisplatin to cancer cells have been prepare..

Cyclodextrin-based supramolecular polymeric nanoparticles for next generation gas separation membranes

S Tan, Q Fu, JMP Scofield, J Kim, PA Gurr, K Ladewig, A Blencowe, GG Qiao

2015-07-28

Cyclodextrin-based supramolecular assemblies derived from poly(dimethylsiloxane) (PDMS) functionalized polyrotaxanes (PRXs) were s..

Visible Light Mediated Controlled Radical Polymerization in the Absence of Exogenous Radical Sources or Catalysts

TG McKenzie, Q Fu, EHH Wong, DE Dunstan, GG Qiao

2015-06-23

The application of external stimuli such as light to induce controlled radical polymerization reactions has important implications..

Functional and Well-Defined β-Sheet-Assembled Porous Spherical Shells by Surface-Guided Peptide Formation

SH Wibowo, A Sulistio, EHH Wong, A Blencowe, GG Qiao

2015-06-01

Polypeptides have attracted widespread attention as building blocks for complex materials due to their ability to form higher-orde..

The role of capsule stiffness on cellular processing

H Sun, EHH Wong, Y Yan, J Cui, Q Dai, J Guo, GG Qiao, F Caruso

2015-06-01

Particle stiffness is emerging as an important parameter in determining the cell uptake dynamics of particles. Understanding the e..

Factors influencing the formation of single-chain polymeric nanoparticles prepared via ring-opening polymerization

EHH Wong, GG Qiao

2015-03-10

The development of single-chain polymeric nanoparticles (SCNP) has been of great scientific interest in recent years. Recently, we..

Fabrication of ultra-thin polyrotaxane-based films via solid-state continuous assembly of polymers

S Tan, E Nam, J Cui, C Xu, Q Fu, JM Ren, EHH Wong, K Ladewig, F Caruso, A Blencowe, GG Qiao

2015-02-07

Surface-confined ultra-thin polyrotaxane (PRX)-based films with tunable composition, surface topology and swelling characteristics..

Degradable cross-linked polymer vesicles for the efficient delivery of platinum drugs

Q Fu, J Xu, K Ladewig, TMA Henderson, GG Qiao

2015-01-07

Nontoxic and acid-degradable cross-linked polymeric vesicles as efficient nanocarriers for the delivery of platinum drugs are repo..

High-performance thin film composite membranes with well-defined poly(dimethylsiloxane)-b-poly(ethylene glycol) copolymer additives for CO2 separation

JMP Scofield, PA Gurr, J Kim, Q Fu, A Halim, SE Kentish, GG Qiao

2015-01-01

A series of well-defined diblock copolymers (BCPs) consisting of poly(ethylene glycol) (PEG) and poly(dimethylsiloxane) (PDMS) wer..

Synthesis of well dispersed polymer grafted metal-organic framework nanoparticles

K Xie, Q Fu, Y He, J Kim, SJ Goh, E Nam, GG Qiao, PA Webley

2015-01-01

Novel polymer grafted metal-organic framework (MOF) nanoparticles were synthesized. The formed core/shell nanoparticles exhibit ou..

Polyimide polydimethylsiloxane triblock copolymers for thin film composite gas separation membranes

PA Gurr, JMP Scofield, J Kim, Q Fu, SE Kentish, GG Qiao

2014-12-01

This article demonstrates the successful fabrication of thin-film-composite (TFC) membranes containing welldefined soft-hard-soft ..

Highly efficient and versatile formation of biocompatible star polymers in pure water and their stimuli-responsive self-assembly

TG McKenzie, EHH Wong, Q Fu, SJ Lam, DE Dunstan, GG Qiao

2014-11-25

This study demonstrates the rapid and efficient formation of functional core cross-linked star polymers via copper-mediated revers..

The effect of soft nanoparticles morphologies on thin film composite membrane performance

Q Fu, EHH Wong, J Kim, JMP Scofield, PA Gurr, SE Kentish, GG Qiao

2014-11-14

Well-defined branched and densely cross-linked soft nanoparticles (SNPs) were synthesized and incorporated into a poly(ether-b-ami..

Fabrication of chiral stationary phases via continuous assembly of polymers for resolution of enantiomers by liquid chromatography

SN Guntari, E Nam, NN Pranata, K Chia, EHH Wong, A Blencowe, TK Goh, F Caruso, GG Qiao

2014-11-01

Precise stereochemical determination of chiral molecules is highly important, especially in the pharmaceutical industry where one ..

Biodegradable and biocompatible poly(ethylene glycol)-based hydrogel films for the regeneration of corneal endothelium

B Ozcelik, KD Brown, A Blencowe, K Ladewig, GW Stevens, JPY Scheerlinck, K Abberton, M Daniell, GG Qiao

2014-09-01

Corneal endothelial cells (CECs) are responsible for maintaining the transparency of the human cornea. Loss of CECs results in bli..

Biocompatible single-chain polymeric nanoparticles via organo-catalyzed ring-opening polymerization

EHH Wong, SJ Lam, E Nam, GG Qiao

2014-06-17

This study presents a novel approach to synthesize biocompatible single-chain polymeric nanoparticles (SCPN) under mild reaction c..

Soft nanoparticles assembled from linear poly(ethylene glycol) and linear brush polydimethylsiloxane diblock copolymers

A Halim, TD Reid, JM Ren, Q Fu, PA Gurr, A Blencowe, SE Kentish, GG Qiao

2014-05-01

A series of novel amphiphilic diblock copolymers composed of hydrophilic linear poly(ethylene glycol) (PEG) and linear brush hydro..

Soft polymeric nanoparticle additives for next generation gas separation membranes

A Halim, Q Fu, Q Yong, PA Gurr, SE Kentish, GG Qiao

2014-04-14

This article highlights a new approach of fabricating a gas separation membrane through the addition of well-defined soft polymeri..

Stereospecific cyclic poly(methyl methacrylate) and its topology-guided hierarchically controlled supramolecular assemblies

JM Ren, K Satoh, TK Goh, A Blencowe, K Nagai, K Ishitake, AJ Christofferson, G Yiapanis, I Yarovsky, M Kamigaito, GG Qiao

2014-01-07

In this study, the stereocomplexation between a novel stereospecific cyclic vinyl polymer, that is, cyclic syndiotactic poly(methy..

Stereospecific Cyclic Poly(methyl methacrylate) and Its Topology‐Guided Hierarchically Controlled Supramolecular Assemblies

Jing Ming Ren, Kotaro Satoh, Tor Kit Goh, Anton Blencowe, Kanji Nagai, Kenji Ishitake, Andrew Joseph Christofferson, George Yiapanis, Irene Yarovsky, Masami Kamigaito, Greg Guanghua Qiao

2014-01-07

<jats:title>Abstract</jats:title><jats:p>In this study, the stereocomplexation between a novel stereospecific cyclic vinyl polymer..

Continuous assembly of polymers via solid phase reactions

E Nam, J Kim, SN Guntari, H Seyler, Q Fu, EHH Wong, A Blencowe, DJ Jones, F Caruso, GG Qiao

2014-01-01

The continuous assembly of polymers in the solid state via ring-opening metathesis polymerization (ssCAP<inf>ROMP</inf>) is report..

Highly porous and mechanically robust polyester poly(ethylene glycol) sponges as implantable scaffolds

B Ozcelik, A Blencowe, J Palmer, K Ladewig, GW Stevens, KM Abberton, WA Morrison, GG Qiao

2014-01-01

The development of suitable scaffolds plays a significant role in tissue engineering research. Although scaffolds with promising f..

Peptide-based star polymers as potential siRNA carriers

SJ Lam, A Sulistio, K Ladewig, EHH Wong, A Blencowe, GG Qiao

2014-01-01

16- and 32-arm star polymers were synthesised using poly(amido amine) (PAMAM) dendrimers as multifunctional initiators for the rin..

Tailoring substrate hydrophilicity using grafted polypeptide nanocoatings

SH Wibowo, A Sulistio, EHH Wong, A Blencowe, GG Qiao

2014-01-01

Peptide nanocoatings with tailored surface-wetting properties were formed on a range of organic (cellulose and cotton) and inorgan..

(Super)hydrophobic and multilayered amphiphilic films prepared by continuous assembly of polymers

SN Guntari, ACH Khin, EHH Wong, TK Goh, A Blencowe, F Caruso, GG Qiao

2013-11-06

The continuous assembly of polymers (CAP) is used to fabricate tailored nanocoatings on a wide variety of substrates. Ring-opening..

Assembly of nanostructured films with hydrophobic subcompartments via continuous assembly of polymers

EHH Wong, MP Van Koeverden, E Nam, SN Guntari, SH Wibowo, A Blencowe, F Caruso, GG Qiao

2013-10-08

The generation of nanoscale polymer films using complex, hierarchically structured (bio)macromolecular architectures has important..

Assembly of free-standing polypeptide films via the synergistic combination of hyperbranched macroinitiators, the grafting-from approach, and cross-chain termination

SH Wibowo, EHH Wong, A Sulistio, SN Guntari, A Blencowe, F Caruso, GG Qiao

2013-09-06

Cross-linked polypeptide-based films are fabricated via a novel and robust method employing surface-initiated ring opening polymer..

Low-fouling, biospecific films prepared by the continuous assembly of polymers

SN Guntari, EHH Wong, TK Goh, R Chandrawati, A Blencowe, F Caruso, GG Qiao

2013-08-12

We report that the continuous assembly of polymers (CAP) approach, mediated by ring-opening metathesis polymerization (ROMP), is a..

The behaviour of honeycomb film formation from star polymers with various fluorine content

Z Zhang, TC Hughes, PA Gurr, A Blencowe, H Uddin, X Hao, GG Qiao

2013-08-02

A series of poly((1H,1H-pentafluoropropyl acrylate)-ran-(methyl methacrylate)) (poly(PFPA-ran-MMA)) star polymers with varying flu..

A novel one-pot approach towards dynamically cross-linked hydrogels

S Tan, A Blencowe, K Ladewig, GG Qiao

2013-06-11

Herein, we report the synthesis of sliding-ring (SR) hydrogel networks in a one-pot click-mediated approach using α,ω-dialkyne pol..

Factors influencing the growth and topography of nanoscale films fabricated by ROMP-mediated continuous assembly of polymers

SN Guntari, TK Goh, A Blencowe, EHH Wong, F Caruso, GG Qiao

2013-01-07

The continuous assembly of polymers (CAP) mediated via ring-opening metathesis polymerization (ROMP) is demonstrated as a simple a..

Highly permeable membrane materials for CO2 capture

Q Fu, A Halim, J Kim, JMP Scofield, PA Gurr, SE Kentish, GG Qiao

2013-01-01

The release of large quantities of CO<inf>2</inf> into the atmosphere has been linked to global warming and climate anomalies. Mem..

Novel drug carriers: From grafted polymers to cross-linked vesicles

J Xu, Q Fu, JM Ren, G Bryant, GG Qiao

2013-01-01

A simple and straightforward method of self-assembling grafted copolymers was developed to fabricate cross-linked polymer vesicles..

Quantitative formation of core cross-linked star polymers via a one-pot two-step single electron transfer-living radical polymerization

EHH Wong, A Blencowe, GG Qiao

2013-01-01

A novel and highly efficient one-pot two-step strategy towards core cross-linked star polymers based on single electron transfer-l..

Phototriggered, metal-free continuous assembly of polymers for the fabrication of ultrathin films

EHH Wong, SN Guntari, A Blencowe, MP Van Koeverden, F Caruso, GG Qiao

2012-08-21

A facile and metal-free thin film fabrication technology based on the photoinduced continuous assembly of polymers (photoCAP) is d..